Diphenhydramine
Diphenhydramine is a medication from the group of antihistamines.
Depending on the amount, Diphenhydramine has the following results on the body:
Antiallergic effect;
Spasmolytic effect;
Antiemetic effect;
Sedative and hypnotic effects;
Local anesthetic;
Reduces swelling due to inflamation related responses (for example, swelling of the mucous tissue layer due to the body respond to bacterial antigens);
Reduces mucous release from the respiration program (by preventing acetylcholine receptors in the anxious system);
Antitussive effect;
Potentiation (strengthening) of the impact of certain medication.
Indications
Diphenhydramine is widely used in medication due to its many results. However, each specific pathology needs different dose and different dose types (tablets, shots, syrups) of Diphenhydramine. Therefore, only the physician can suggest a suitable therapy option for you.
Diphenhydramine is used:
Against any allergic reactions (rash, angioedema, pruritus, urticaria, dermatitis, anaphylactic surprise, hypersensitive rhinitis and conjunctivitis, bronchial asthma);
As a hypnotic and sedative;
As a solution for soothing the sleek muscles in order to stop spasm, and for growing the veins to decrease blood veins pressure;
To decrease the swelling and swelling of the epidermis and mucous walls, and the capillary leaks in the structure (used both systemically and topically by means of a gel, for example, to reverse the consequences of pest bites);
As an antiemetic (especially for nausea or vomiting of maternity and sea sickness);
As a medication with an antitussive effect;
Sometimes for Parkinson’s disease, chorea, hemorrhagic vasculitis, serum illness, blood veins transfusions, and for regional sedation in highly hypersensitive individuals;
To enhance the healing results of other medication.
Side effects
Most typical results of Diphenhydramine:
Weakness, sleepiness, such as during the day;
Increased viscosity of sputum (when coughing), problems hacking and coughing.
Less typical adverse responses of Diphenhydramine:
Headache or dizziness;
Fatigue, and weakness;
Low blood veins pressure;
Dryness in the oral cavity or nose paragraphs.
Rare part effects
Tachycardia;
Dilated students, blurry perspective, reduced sharpness of vision;
Ringing in the ears;
Increased understanding of the epidermis to UV light;
Increased perspiration, nervousness;
Difficult or agonizing urination;
Increased stomach peristalsis, nausea or vomiting, nausea or vomiting, diarrhoea or bowel problems, stomach discomfort due to muscle spasms of the sleek muscle;
Agitation, excitement.
If you develop any of the adverse responses of Diphenhydramine, review them to your physician.
Serious part effects
Severe tachycardia, infrequent heart function, discomfort in the chest;
Hallucinations, unsuitable actions, trouble sleeping, cramps;
Allergic responses – itchiness, swelling of the mouth, eye lids, neck, and larynx, urticaria, extreme of the epidermis, breathlessness or swallowing;
Increased blood reduction. Separated cases: blood reduction from abdomen sores – blood veins in the feces or nausea or vomiting blood veins.
Serious adverse responses of Diphenhydramine are unusual, but when they happen, you should instantly search for treatment.
Laboratory abnormalities
Agranulocytosis, thrombocytopenia, and hemolytic anemia are sometimes seen in blood veins assessments during therapy with Diphenhydramine.
Withdrawal syndrome
Addiction and following drawback problem of Diphenhydramine may happen in the event of extended misuse of large dose of Diphenhydramine medicines. If we follow the suggested daily amount, length, and number of consumption, then the risk of drawback problem will tend to zero. If you discover you have drawback signs, instantly search for treatment.
Possible signs of drawback syndrome:
Insomnia;
Restlessness and anxiety;
Upset abdomen.
Side results in children
Drowsiness, improved depressive conditions and tearfulness are the most typical adverse responses of Diphenhydramine in kids. Drugs containing Diphenhydramine may be applied only when there are signs for such. Since the mass of kid's human is less than that of grownups, they require personal amount titration selection and its dose type.
Side results during maternity and breast-feeding
Drugs containing Diphenhydramine can be taken by expectant mothers, but only under healthcare guidance and if there are clear signs. Long-term therapy with great dose of the medication in a expectant mother may cause drawback problem in the baby.
Diphenhydramine can restrict the release of breasts dairy. Besides, it goes into breasts dairy, and thus the baby may suffer from such adverse responses as sleepiness, sleepiness or more serious adverse responses. It is therefore suggested to keep from breast-feeding during therapy.
Side results in women
There were isolated situations of females who experienced early start of monthly periods during therapy with Diphenhydramine.
Side results in men
There were periodic situations of men who had increased prostate during the use of Diphenhydramine.
Side results in the elderly
Dizziness, sleepiness, and reduced hypertension are the most typical adverse responses in the seniors. However, there are also situations of all the other adverse responses described above. Since the threats of having heart illnesses increase with age, and many senior citizens regularly take medicines, it is necessary to seek advice from a physician before beginning therapy with Diphenhydramine. The physician will choose the right amount and will decide whether it is suitable with other medicines and safe for your wellness.
Overdose
Most typical warning signs of Diphenhydramine overdose:
Dizziness or headache;
Severe drowsiness;
pronounced general weakness;
Dry mouth;
Loss of consciousness;
Nausea and vomiting;
Ataxia.
You should quickly search for treatment once there is any sign of over dose or you suppose an over dose has happened.
Warnings and recommendations
Tell your physician if you are taking any other medicines (anticholinergics , anxiolytics, pain killers, sedative drugs and antidepressant medications, etc.), and be sure to name all the medication. This is necessary because Diphenhydramine can enhance not only the main results but also the adverse responses of some medication, thus being a risk to health;
Tell your physician before beginning therapy if you are suffering from any allergic reactions, bronchial bronchial asthma certain kinds of glaucoma, prostate augmentation, psychological conditions, ulcer of the abdomen or digestive system, complications with urinating and other related conditions;
To prevent wooziness stand up gradually, especially in the first days of therapy.
Be cautious when driving a car or performing a work that needs great precision and focus, as Diphenhydramine can slow down the response rate and damage the ability to focus.
Diphenhydramine and alcohol
It is recommended to avoid liquor, especially great dose of liquor during therapy with Diphenhydramine. This is so because this medication can enhance the inhibitory impact of liquor on the neurological program. This can cause depressive conditions, troublesome actions, serious sleepiness and lack of alignment (depending on the amount of liquor and personal sensitivity). In addition, Diphenhydramine may enhance the destructive impact of liquor on the liver organ.
