Avelox


Avelox is the brand name of the medication whose ingredient is moxifloxacin. This is a fluoroquinolone anti-bacterial agent. It has bactericidal action (kills microbes).


It is effective against many gram-positive and gram-negative parasites, atypical, acid-fast and anaerobic parasites, such as Staphylococcus, Streptococcus, Klebsiella, Enterobacteria, Clostridia and Mycoplasm.

Indications

Avelox is used in adults to treat such contagious and inflamation related illnesses as:

Community-acquired pneumonia.
Acute sinus problems.
Exacerbation of serious respiratory disease.
Uncomplicated and complex attacks of the epidermis and soft tissues (including contaminated suffering from diabetes foot).
Uncomplicated pelvic inflamation related illnesses (endometritis, salpingitis, etc.).
Complicated intra-abdominal attacks (peritonitis, intra-abdominal abscess).
Side effects

When using Avelox, the most frequently noticed part results are the following:

Digestive system: stomach pain, nausea or nausea, nausea, diarrhoea, bowel problems, unwanted gas.
Nervous system: headache, wooziness.
Senses: flavor problem.
Intravenous management of the medication may lead to swelling, swelling and pain at the injection site.

The part results are usually light to average and do not require stopping of the medication.

Allergies to Avelox may reveal in the form of itchiness, cities, and hardly ever – angioedema. In unusual situations, there may be serious hypersensitive reactions such as anaphylaxis, toxic skin necrolysis and Stevens-Johnson syndrome.

Rare part effects

In some situations, the following part results are noticed when getting Avelox:

Cardiovascular system: eliminating, improved pulse rate, increase or loss of hypertension, passing out.
Respiratory system: difficulty breathing.
Digestive system: anorexia, stomatitis, difficulty ingesting.
Nervous system: uneasiness, stress, improved exercising, insomnia, sensation of tingling, reduced or improved understanding, incapacity in adequate perception of stimulating elements (for example, a sense of pain when experiencing stress, exposure to cold or heat), shaking divisions, sleepiness, abnormal dreams, vertigo (loss of balance, which is combined with a sensation that the outside world or someone’s own body is spinning round), poor sychronisation, affected interest, depersonalization, and emotional uncertainty.
Senses: double perspective, decrement in visual skill, blurry perspective, smell conditions, ears ringing, lack of flavor understanding.
Musculoskeletal system: pain in joints and muscles, improved muscle.
Hematopoietic system: anemia.
Others: sweating, malaise, swelling.
Serious part effects

Severe part results when using Avelox are noticed rarely. There is an urgent need to search for therapy when these responses occur:

Cardiovascular system: arrhythmia.
Respiratory system: asthma suffering situation.
Digestive system: not eating due to lack of appetite, gastroenteritis, pseudomembranous colitis (fever, pains stomach pain, frequent watering stools), liver disease, jaundice.
Nervous system: psychosis, hallucinations, depression, forgetfulness, affected conversation, convulsions, frustration (very excited, which is combined with stress, fear, conversation or motor restlessness).
Musculoskeletal system: tendinitis (inflammation of the tendon), muscle crack, step problem due to damage to the bone and joint program, arthritis.
Urinary system: lack of fluids due to diarrhoea or loss of liquid intake; renal impairment; renal failing.
There were separated situations of phlebitis after medication management of the medication.

In some situations, especially with extended use and great dosage of the medication, there may be candidal superinfection – fungus attacks of various organs such the epidermis, claws, scalp, mucous walls, upper breathing system, breathing system, bladder and digestive system. To be able to prevent these problems, you should totally follow the physician's suggestions with respect to amount and duration of getting the medication. You should immediately search for therapy if you suppose a infection.

Changes in clinical parameters

During avelox therapy, there are possible erythropenia, leukopenia, thrombocytosis, thrombocytopenia, prolongation of prothrombin time, change in focus tromoplastina, changes in the focus of prothrombin, great stages of bilirubin and amylase, great stages of alkaline phosphatase and gamma-glutamyl transpeptidase, temporary heights in ALT and AST, hyperuricemia, hyperglycemia, hyperlipidemia.

Side results in children

The protection of avelox in kids is not yet known. Therefore, the medication is not recommended to sufferers under 18 years old.

Side results in women

Women create yeast vaginitis quite often when getting Avelox. The physician should be informed if you have any goofy release, pain, itchiness, and pain in the area of the vaginal canal and vulva during therapy with this medication.

Side results during maternity and breast-feeding

The protection of avelox during maternity and lactation is not yet known. Therefore, the medication is not recommended to pregnant and nursing females.

Side results in the elderly

While getting Avelox, the seniors, especially those with renal disease, more often than other groups of sufferers create renal incapacity and renal failing.

Elderly sufferers have improved chance of harm from a fall due to ataxia, and improved chance of tendinitis and muscle crack (especially in sufferers receiving glucocorticosteroids).

It should be mentioned that such problems are unusual. Reducing the amount of the medication is normally not required.

Warnings and recommendations

Before starting therapy with avelox, it is necessarily to inform the physician of all serious illnesses, especially illnesses of the neurological program that are combined with convulsions, liver organ illnesses, arrhythmias, and serious pelvic inflamation related illnesses.

Tell your physician about all drugs that you are getting or plan to take, especially other anti-microbial medication, glucocorticosteroids, antacids, mineral buildings, and multi-vitamin arrangements.

If you had hypersensitive reactions to any medication in the past, you also need to inform your physician, especially if you are hypersensitive to avelox, moxifloxacin and other fluoroquinolone anti-microbial agents (sparfloxacin, levofloxacin, ciprofloxacin, ofloxacin, lomefloxacin, trovafloxacin, gatifloxacin, gemifloxacin, etc.).

Avelox hardly ever causes part results in the neurological program. However, if you are going to drive vehicles or operate moving equipment during the period of therapy, it is necessary to inform the physician for him to evaluate your situation and decide whether such actions are allowed.

Avelox and alcohol

There is currently no data on the common influence of Avelox and liquor. However, note that both avelox and liquor are digested in the liver organ. To avoid excessive load on the liver organ, it is recommended to limit the use of liquor when getting this medication.