Ativan
Ativan is antianxiety medication of diazepam group. It has sedative, anticonvulsant and rest action, cause miorelaxation.
It can be recommended in such cases: stress, neuroses, despression signs, panic attacks, manic state, serious addict delirium, epilepsy (including position epilepticus), convulsion, climacteric conditions, psychosomatic conditions, sleeplessness, migraine headache and complications.
Effects of Ativan are dose-dependent.
Side effects
Ativan connected to the medication that are released totally on prescription. And its adverse responses usually due to amount excessing over suggested.
Neurological part effects: rest, common weak point, frustration, wooziness, sleepiness, confusion, slurred conversation, frustration, violence, unsteadiness, shaking, unsuitable actions, hallucinations, anterograde amnesia, tremors
General part effects: blurry perspective, issues, skin allergy, dry mouth, muscle weak point, flu-like problem (shivering, fever), improved bleeding
Gastro-intestinal part effects: nausea or nausea, nausea, stomach pain, stomach pain, bowel problems, diarrhea
Genito-urinal part effects: reduced sexual operate, bladder disorder
Serious part effects
If you encounter any of serious complication during Ativan consumption you should call your doctor and look for treatment instantly.
Severe emotional conditions (including the appearance of taking once life actions in sufferers being affected by depressive disorders)
Respiratory despression signs (dangerous because breathing may stop)
Depression of the additional (hypotension, reduced heart rate)
Atrial fibrillation or other heart arrhythmias
Repression of ingesting reflex
Hallucinations
Anterograde amnesia
Dangerous allergies (swelling of the face, mouth, mouth, neck, anaphylactic shock)
Laboratory changes
Possible clinical changes during Ativan consumption include:
Leukopenia
Increased lactate
Anemia
Neutropenia
Pancytopenia
Withdrawal syndrome
Ativan can cause habit, even when used in healing dosage, and this is verified by the overall look of emotional and physical signs that happen after amount decrease or drawback of Ativan. Usually, habit signs begin to appear after 6 or more months of Ativan consumption. Booze improves the chance of habit.
Withdrawal problem is recognized by the following symptoms:
Insomnia
Headache
Dizziness
Tremor
Irritability
Mental confusion
Anxiety
Hyperacusis
Numbness or prickling in the extremities
Sweating
Nausea
Loss of appetite
Vomiting
Diarrhea
As a symptom of drawback problem, sleeplessness can happen just a week after taking Ativan.
Side results in children
Ativan should not be used in kids younger than 12 years. In teenagers, the medication causes the same adverse responses as in grownups. It should also be carried in mind that in kids, removal of Ativan is more slowly than in grownups, and therefore the chance of adverse responses is greater.
Side results in expecting women
According to the type of medication for expectant mothers (FDA), the medication is categorized as Classification D (dangerous). Some diazepam can go through through the placenta. They are also found in small amounts in breast dairy. It is especially not suggested to use Ativan in the first trimester of maternity (it considerably improves the chance of birth problems and decreases success rate), as well as during lactation because of the likelihood of the overall look of the same adverse responses as in grownups.
Side results in the elderly
Sensitivity to Ativan is greater in the seniors than in adolescents. This is due to such factors as high understanding of receptors of the nerve program, decrease in metabolic rate and amount of removal of the medication. Therefore, senior citizens encounter a more noticeable nerve program despression signs, and often have serious adverse responses. However, in comparison with other diazepam (such as midazolam and diazepam), Ativan relatively causes less adverse responses in seniors sufferers.
Overdose of Ativan
Most often, over dose of Ativan happens when it is along with liquor or other medication.
Symptoms of overdose:
CNS despression signs in different levels (from somnolence to coma) – relies on the dose
Respiratory depression
Inhibition of heart activity
Paradoxical excitation (occurs mainly in emotional sufferers, the seniors and kids, and consist of such signs as frustration, enjoyment, problems, talkativeness, tremor, rage, rage, stress, improved reflexes)
Confusion of speech
Warnings and recommendations
Caution should be taken when used in sufferers being affected by obstructive rest apnoea problem, and sufferers with serious obstructive lung disease, if closed-angle glaucoma, epilepsy, serious despression signs, porphyria, psychosis and primary despression signs are alleged.
Because Ativan is biotransformed mainly in the liver organ, noticeable incapacity of liver organ operate decelerates the metabolic rate of Ativan. In this case, rest is mainly increased and extended. During kidney illnesses, along with hyperproteinuria, the impact of Ativan might also improve.
The sedative-hypnotic results of Ativan improve in sufferers receiving medication that press the nerve program (other sedative drugs, hypnotics, anticonvulsant medication, neuroleptics and antidepressants). Such medication as erythromycin, omeprazole, cimetidine, fluconazole, diltiazem, verapamil, ketoconazole and itraconazole slow down the removal of most diazepam, such as Ativan, from the body.
Contraindications of Ativan
myasthenia gravis
severe renal-hepatic failure
closed-angle glaucoma
acute inebriation with psychotropic drugs
hypersensitivity to the drug
Ativan and alcohol
Persons who misuse liquor and medication may develop patience to Ativan and encounter peculiar excitation. In comparison, intensification of the impact of Ativan is more likely in individuals who are under the impact of liquor.
