Aspirin

Discomfort killers (acetylsalicylic acid) is a medication that has medication, anti-inflammatory and antipyretic results. It stops blood vessels clots – development of thrombus.


Indications

As an analgesic

Aspirin is prescribed for light and average inflamation related and non-inflammatory pain, especially during frustration (including the one caused by hangover syndrome), tooth ache, headaches, neuralgia, chest radicular problem, lumbago, pains in joints and muscles, and painful monthly periods.

As an antipyretic and anti-inflammatory drug

Used during febrile problem caused by various typical contagious and inflamation related illnesses (tonsillitis, pneumonia, etc.) and local inflamation related processes (infected injuries, infections, etc.).

Presently not used during arthritis, rheumatism and other rheumatic illnesses. The reason is that it is a characteristic medication and does not affect the course of illness, but it can cause serious side effects which improve under extend use of the medication.

As an antiaggregant

As a medication that stops thrombus, it is used in the treatment of center, instable angina, persistent temporary cerebral ischemia and ischemic stroke in men, during aortoarteritis (Takayasu’s disease), atherosclerotic center (Kawasaki disease), heart fibrillation, mitral device illness, lung infarction, repeated lung thromboembolism, serious trombophlebitis and Dressler’s problem.

Under myocardial infarction, the medication is used to prevent repeated heart arrest. Prophylactically, aspirin is used during mitral device prolapse (a reduced chance of thromboembolism), center device prosthetics (reducing the chance of thromboembolism), increase coronary angioplasty and stent installation (reducing the chance of repeated stenosis).

Side effects

The most typical reactions are side effects on the digestive tract: symptoms of heartburn, nausea or nausea, nausea, pain in the stomach, symptoms of heartburn, and diarrhoea. Due to the aggravating effect of aspirin on the mucous tissue layer, there may be stomach and duodenum erosions. Moreover, the medication can cause digestive blood vessels loss (including invisible ones).

Aspirin improves the chance of blood vessels loss. There may be stomatorrhagia, lose blood, nosebleeds, and blood vessels loss from the urinary system. Surgery improves the occurrence of blood vessels loss, both during functions and in the postoperative period. Due to increased invisible and non-hidden blood vessels loss, there may be growth of serious or serious posthemorrhagic anemia.

With extended use and over dose, there may be frustration, wooziness, ear noise and blurry vision, temporary kidney and liver organ malfunction.

Rare part effects

Some of the unusual side effects include growth of stomach and duodenal sores, interstitial nephritis and papillary necrosis.

Allergy to the medication can be demonstrated in the form of skin rashes, cities, itchiness, swelling of the mucous walls of the nose, allergic rhinitis. There may be Quincke’s swelling, bronchospasm, and in serious situations anaphylactic shock.

Serious part effects

In some situations, the affected person is affected with perforating stomach and duodenal sores, as well as life-threatening massive blood vessels loss. Reye’s problem (a mixture of encephalopathy and serious fatty liver organ with liver organ failure) is another unusual serious adverse reaction. There were also some situations of aseptic meningitis, nephrotic problem and serious kidney failing.

In some situations, “aspirin” bronchial asthma and “aspirin triad” (bronchial bronchial asthma along with repeated nose polyposis and paranasal nose polyposis, and with intolerance of pirazolon derivatives) may develop during the medication use.

Changes in clinical tests

Large and average dosage improve the levels of the crystals. Bleedings may lead to anemia. In some situations, there may be thrombocytopenia, level of liver organ transaminases.

Side results during maternity and lactation

Aspirin should not be used in the first and third trimester of maternity. Occasional use is allowed in the second trimester, but long-term therapy is disallowed.

The medication has teratogenic results. When taken in the first trimester, the upper taste of the unborn infant may split. Taking it in the third trimester improves the chance of premature closing of the ductus arteriosus, lung general hyperplasia and lung high blood pressure. There may also be kidney malfunction, in some situations – with kidney failing. Moreover, the medication improves the chance of cryptorchidism, prevents labor, and improves the chance of blood vessels loss in the mother and newborn. All of these results can be observed even at reduced dosage of the medication.

During nursing, aspirin is contraindicated, as the medication and its breaking products are eliminated into the breast milk products in small dosage.

Side results in children

Children under 12 years old should not use the medication because under infections, aspirin improves the chance of Reye’s problem.