1
Tegretol side effects (carbamazepine) common adverse reactions are dizziness, drowsiness,
fatigue, nausea, vomiting, occasional granulocytes reduce reversible
thrombocytopenia, and even cause aplastic anemia and toxic hepatitis, it is in
the
start of treatment (especially a month) should regularly check
blood.
Occasional allergic reactions. It is reported that two cases had severe allergic reaction, one cases larger?? The necrotic epidermal necrolysis, drug eruption, the other was a heavy-duty erythema multiforme type drug eruption. Be immediately discontinued, and active anti-allergy treatment.
3 can be caused by hypothyroidism.
4 large doses, can cause atrioventricular block, should control the dose.
Heart, liver, renal insufficiency and early pregnant women, lactating women hanged, severe glaucoma, cardiovascular diseases and elderly patients with caution. The long-term application need to regularly check blood, liver function and urine.
7 case reports, aplastic anemia and agranulocytosis related to the drug. The average incidence of agranulocytosis per million per year to 4.7 cases of aplastic anemia average annual per million people for two cases. Transient or sustained platelet and white blood cell count is reduced to occasional or common in the drug treatment, but most had not necessarily aplastic anemia and agranulocytosis. Before taking the drug, a complete blood count, including platelet count, if possible detection reticular cells and plasma iron, as a reference baseline. Although the significance of hematologic monitoring is controversial, but the authority is still recommended: in the first months of the medication, weekly blood tests; checked once a month within the next five months, after 2-4 times per year.
8 during treatment if the white blood cells or platelets significantly reduced, should closely monitor the patient and monitoring of the red blood cell count of whole blood, significant bone marrow suppression, should immediately stop taking the drug. Any serious symptoms or signs of skin reactions (such as Stevens-Johnson syndrome, Lyell's syndrome), should immediately stop taking the medication. The drug should be administered under the supervision of a doctor. Accompanied by atypical absence seizures in patients with mixed epilepsy particularly careful. Because the drugs can be triggered from the systemic increase in the frequency of seizures. If the attack intensifies, should stop taking the drug. Hematologic signs and symptoms of poisoning may occur should tell patients early, as well as skin and liver reaction symptoms. If so, the following reaction, such as fever, sore throat, rash, mouth ulcers, easy bruising, petechiae or purpura occurs, patients should tell your doctor immediately.
9 is a history of heart disease, liver disease and kidney disease, a history of hematologic adverse reactions to other drugs, or interrupt the drug treatment, and should after weighing the pros and cons before prescribing, and intensive care patients. Check liver function before taking carbamazepine should the medication during liver function should be checked regularly, especially for a history of liver disease and in elderly patients. Medication during increased liver dysfunction or active liver disease occurs, immediately stop taking the drug. Proposed periodic complete urinalysis and BUN check the medication before and during the medication. Mild skin reactions, such as spots or rash, this should usually transient and harmless, reduce the dose or medication shall remain within days or weeks away on its own. Needed intensive care patients. The drug mild anticholinergic effects during treatment of patients with elevated intraocular pressure, treatment in intensive care. The drug can activate the potential psychosis attack on elderly patients can cause confusion or agitation. Individual case reports, the occurrence of the the male fecundity damage or abnormal spermatogenesis, but whether the drug has not yet conclusive. Reported that women using oral contraceptives breakthrough bleeding occurs, the drug may affect the reliability of oral contraceptives. Carbamazepine dose and plasma concentration, the relationship between the plasma concentration and clinical efficacy or tolerability inaccurate, but monitoring of the blood concentration of the following situations may be helpful: When the seizure frequency suddenly increased or check whether the patient was ordered medication; pregnancy; children and young people during the medication; suspected malabsorption; suspected poisoning caused by concomitant medications. For immediate stop taking the drug should be used, before switching to the new anti-epileptic drugs, other suitable transitional drugs (such as diazepam intravenously or rectally; intravenous phenytoin).
10. Response capability of the driver or machine manipulator: the drug may cause dizziness, drowsiness, affect the patient's ability to respond, especially in the initial medication or dose adjustment.
Occasional allergic reactions. It is reported that two cases had severe allergic reaction, one cases larger?? The necrotic epidermal necrolysis, drug eruption, the other was a heavy-duty erythema multiforme type drug eruption. Be immediately discontinued, and active anti-allergy treatment.
3 can be caused by hypothyroidism.
4 large doses, can cause atrioventricular block, should control the dose.
Heart, liver, renal insufficiency and early pregnant women, lactating women hanged, severe glaucoma, cardiovascular diseases and elderly patients with caution. The long-term application need to regularly check blood, liver function and urine.
7 case reports, aplastic anemia and agranulocytosis related to the drug. The average incidence of agranulocytosis per million per year to 4.7 cases of aplastic anemia average annual per million people for two cases. Transient or sustained platelet and white blood cell count is reduced to occasional or common in the drug treatment, but most had not necessarily aplastic anemia and agranulocytosis. Before taking the drug, a complete blood count, including platelet count, if possible detection reticular cells and plasma iron, as a reference baseline. Although the significance of hematologic monitoring is controversial, but the authority is still recommended: in the first months of the medication, weekly blood tests; checked once a month within the next five months, after 2-4 times per year.
8 during treatment if the white blood cells or platelets significantly reduced, should closely monitor the patient and monitoring of the red blood cell count of whole blood, significant bone marrow suppression, should immediately stop taking the drug. Any serious symptoms or signs of skin reactions (such as Stevens-Johnson syndrome, Lyell's syndrome), should immediately stop taking the medication. The drug should be administered under the supervision of a doctor. Accompanied by atypical absence seizures in patients with mixed epilepsy particularly careful. Because the drugs can be triggered from the systemic increase in the frequency of seizures. If the attack intensifies, should stop taking the drug. Hematologic signs and symptoms of poisoning may occur should tell patients early, as well as skin and liver reaction symptoms. If so, the following reaction, such as fever, sore throat, rash, mouth ulcers, easy bruising, petechiae or purpura occurs, patients should tell your doctor immediately.
9 is a history of heart disease, liver disease and kidney disease, a history of hematologic adverse reactions to other drugs, or interrupt the drug treatment, and should after weighing the pros and cons before prescribing, and intensive care patients. Check liver function before taking carbamazepine should the medication during liver function should be checked regularly, especially for a history of liver disease and in elderly patients. Medication during increased liver dysfunction or active liver disease occurs, immediately stop taking the drug. Proposed periodic complete urinalysis and BUN check the medication before and during the medication. Mild skin reactions, such as spots or rash, this should usually transient and harmless, reduce the dose or medication shall remain within days or weeks away on its own. Needed intensive care patients. The drug mild anticholinergic effects during treatment of patients with elevated intraocular pressure, treatment in intensive care. The drug can activate the potential psychosis attack on elderly patients can cause confusion or agitation. Individual case reports, the occurrence of the the male fecundity damage or abnormal spermatogenesis, but whether the drug has not yet conclusive. Reported that women using oral contraceptives breakthrough bleeding occurs, the drug may affect the reliability of oral contraceptives. Carbamazepine dose and plasma concentration, the relationship between the plasma concentration and clinical efficacy or tolerability inaccurate, but monitoring of the blood concentration of the following situations may be helpful: When the seizure frequency suddenly increased or check whether the patient was ordered medication; pregnancy; children and young people during the medication; suspected malabsorption; suspected poisoning caused by concomitant medications. For immediate stop taking the drug should be used, before switching to the new anti-epileptic drugs, other suitable transitional drugs (such as diazepam intravenously or rectally; intravenous phenytoin).
10. Response capability of the driver or machine manipulator: the drug may cause dizziness, drowsiness, affect the patient's ability to respond, especially in the initial medication or dose adjustment.
