Zocor

Zocor Simvastatin Tablets, mainly for hyperlipidemia. Simvastatin generally well tolerated, a slight majority of adverse reactions were transient. Fewer than 2% of patients in controlled clinical trials, adverse reactions due to simvastatin half-way stop.According to reports, the ring sokdam Zocor side effects: nausea, diarrhea, skin rashes, indigestion, itching, hair loss, dizziness, muscle cramps, myalgia, pancreatitis, paresthesia, peripheral neuropathy, vomiting and anemia and so on.Primary hypercholesterolemia, heterozygous familial
hypercholesterolemia or mixed hypercholesterolemia patients, when diet and other non-drug treatment is not ideal, simvastatin can be used to reduce elevated total cholesterol low-density lipoprotein cholesterol, apolipoprotein B, and triglycerides. And simvastatin increased high-density lipoprotein cholesterol, thereby lowering low-density lipoprotein / high-density lipoprotein, and total cholesterol / HDL ratio.Zocor's usageGeneral before serving daily dose of 10mg, the evening serving Dayton. Patients with mild to moderately elevated cholesterol levels, daily dose of 5mg before serving. To adjust the dose interval should be more than four weeks, the maximum daily dose 40mg evening serving Dayton. When the low-density lipoprotein cholesterol levels dropped to 75mg/dL (1.94mmol / L) or total cholesterol level dropped to 140mg/dL (3.6mmol / L) or less, you should reduce the dose of simvastatin.Note Zocor1, patients receiving simvastatin treatment previously accepted standard cholesterol diet and continue to use in the course of treatment.2, livers reaction. This drug should be used with caution in the consumption of alcohol and / or a history of liver disease patients. Active liver disease or unexplained elevated aminotransferase simvastatin should be banned. In clinical trials, there is a small number of patients taking simvastatin significant persistently elevated serum aminotransferase (more than 3 times more than normal) phenomenon. After stopping the aminotransferase enzyme can be restored to the level before treatment, but no jaundice or other clinical symptoms or signs, nor allergy. Should strengthen inspection and to pay more attention aminotransferase enzymes elevated in patients before treatment is recommended. If the patient aminotransferase performance continues to rise, especially aminotransferase enzymes than normal more than 3 times and maintain a sustained, you should be stopping. The same as with other lipid-lowering drug, simvastatin treatment in patients with amino transferase moderately elevated (3-fold lower than normal) were also reported. These changes usually after simvastatin treatment soon there, but generally as a transient and not accompanied by any symptoms, so do not stop.3, muscle reaction. Simvastatin treated patients generally creatine kinase (CK, from skeletal muscle) and a transient increase slightly, but did not have any clinical significance. Diffuse myalgia, muscle weakness or / and elevated creatine kinase (CK) (greater than normal times), should be considered as myopathy, and should therefore be patient if found not to be construed above myopathy signs should tell your doctor immediately. Found a significant increase in creatine kinase (CK) or diagnosed or suspected myalgia, should immediately stop simvastatin treatment. For acute or severe conditions implied myopathy and rhabdomyolysis secondary acute renal failure tendency of patients should be stopped methyl hydroxyl glutaryl coenzyme A (HMG-CoA) reductase inhibitor therapy.4, Ophthalmology check. Even in the absence of any drug treatment, with a clouding of the lens of the incidence of age will also increase, long-term clinical studies show no adverse effect of simvastatin on human lens.5 homozygous familial hypercholesterolemia. Due to the complete lack sake of low-density lipoprotein (LDL) receptor, in patients with homozygous familial hypercholesterolemia, the effect of simvastatin treatment of such patients is not good enough.6, high triglyceride level viremia. Simvastatin only moderate the effect of lowering triglycerides, not suitable for the treatment of elevated triglyceride based exceptions (such as Ⅰ, Ⅳ, Ⅴ type hyperlipidemia).Excessive alcohol drinking and / or past the liver medical history of patients should be careful to use the product.